Award-Winning Vertical Mouse in Natural Handshake Position

The Evoluent VerticalMouse 4 is the original and most trusted vertical mouse—recommended by ergonomists and hand surgeons worldwide for eliminating mouse-related wrist pain, carpal tunnel syndrome, and RSI through its patented natural handshake positioning.

Why Evoluent is the #1 Vertical Mouse

• Patented Handshake Position: 78° vertical angle maintains natural forearm rotation, eliminating wrist pronation that causes carpal tunnel and RSI
• Contoured Shape: Precision-molded to support hand anatomy—prevents gripping and reduces muscle strain during extended use
• 6 Programmable Buttons: Thumb buttons, side buttons, and scroll wheel provide full mouse functionality without awkward finger stretching
• Adjustable Pointer Speed: Toggle between 4 DPI settings (800/1300/1800/2600) without software—instant precision control
• Extended Lip: Prevents pinky finger from dragging on desk surface, eliminating friction and contact stress

Clinical Benefits for Wrist Pain & RSI

Traditional mice force wrist pronation (palm-down position) that twists forearm bones and compresses the median nerve—the primary cause of carpal tunnel syndrome and mouse-related RSI. The Evoluent's vertical design maintains neutral forearm rotation, reducing muscle strain by up to 70% and preventing cumulative trauma during extended computer use. Thousands of RSI sufferers have eliminated chronic pain by switching to the Evoluent VerticalMouse.

Trusted by Medical Professionals

Recommended by occupational therapists, hand surgeons, and ergonomists since 2002. The Evoluent VerticalMouse has helped tens of thousands of office workers, programmers, designers, and computer professionals eliminate chronic wrist pain and prevent surgery.

Who It's Built For

Essential for anyone experiencing wrist pain, forearm strain, carpal tunnel symptoms, or RSI from traditional mouse use. Ideal for office professionals, graphic designers, programmers, CAD operators, gamers, and anyone spending 4+ hours daily with a mouse. Particularly effective for post-injury recovery and preventing chronic conditions in high-risk computer users.

Technical Specifications

• Patented 78° vertical handshake angle
• Contoured ergonomic shape with extended lip
• 6 programmable buttons (left, right, middle, 2 thumb, 1 side)
• Adjustable DPI: 800/1300/1800/2600 (toggle button)
• Optical sensor for precise tracking
• USB wired connection (plug-and-play)
• Compatible with Windows, Mac, Linux
• Available in right-hand and left-hand versions
• Available in regular and small sizes
• Cable length: 6 feet

Size & Hand Selection Guide

Hand Size (measure from wrist crease to tip of middle finger):

• Small (VM4S): Up to 7 inches (178mm) - Ideal for smaller hands, youth, petite users
• Regular (VM4): 7+ inches (178mm+) - Standard size, fits majority of users

Hand Dominance:

• Right-Hand (VM4R): Most popular, designed for right-hand use
• Left-Hand (VM4L): Mirror design for left-handed users

What's Included

• Evoluent VerticalMouse 4
• USB cable (6 feet)
• Quick start guide
• Button programming instructions

Button Programming (Optional)

All 6 buttons are fully programmable using free Evoluent Mouse Manager software (Windows/Mac). Assign custom functions, keyboard shortcuts, or macros to any button for enhanced productivity. Works plug-and-play without software for standard mouse functions.

Adaptation Period

Most users adapt to vertical mouse positioning within 3-5 days. Start with short sessions (30-60 minutes) and gradually increase usage as your hand adjusts to the natural handshake position. Pain relief typically begins within the first week of consistent use, with maximum benefit achieved after 2-3 weeks.

Why Evoluent Outperforms Other Vertical Mice

Unlike generic vertical mice, the Evoluent features patented contoured shaping that prevents gripping, extended lip protection for pinky finger, and precision optical tracking. The 78° angle is clinically optimized for maximum forearm rotation relief without compromising usability. Over 20 years of ergonomic research and refinement make the Evoluent the gold standard in vertical mouse design.

Award-Winning Design

Winner of multiple ergonomic design awards including the Arthritis Foundation Ease-of-Use Commendation. Featured in ergonomic journals, medical publications, and recommended by leading hand surgeons and occupational health specialists worldwide.

Premium Quality & Warranty

Manufactured by Evoluent with rigorous quality control and durable construction. Each VerticalMouse 4 is backed by a 2-year manufacturer warranty and designed for years of daily professional use.

Free shipping on orders over $50. 2-year warranty. Right & left hand options. Regular & small sizes available.