Award-Winning Vertical Mouse in Natural Handshake Position

The Evoluent VerticalMouse 4 is the original and most trusted vertical mouse—recommended by ergonomists and hand surgeons worldwide for eliminating mouse-related wrist pain, carpal tunnel syndrome, and RSI through its patented natural handshake positioning.

Why Evoluent is the #1 Vertical Mouse

• Patented Handshake Position: 78° vertical angle maintains natural forearm rotation, eliminating wrist pronation that causes carpal tunnel and RSI
• Contoured Shape: Precision-molded to support hand anatomy—prevents gripping and reduces muscle strain during extended use
• 6 Programmable Buttons: Thumb buttons, side buttons, and scroll wheel provide full mouse functionality without awkward finger stretching
• Adjustable Pointer Speed: Toggle between 4 DPI settings (800/1300/1800/2600) without software—instant precision control
• Extended Lip: Prevents pinky finger from dragging on desk surface, eliminating friction and contact stress

Clinical Benefits for Wrist Pain & RSI

Traditional mice force wrist pronation (palm-down position) that twists forearm bones and compresses the median nerve—the primary cause of carpal tunnel syndrome and mouse-related RSI. The Evoluent's vertical design maintains neutral forearm rotation, reducing muscle strain by up to 70% and preventing cumulative trauma during extended computer use. Thousands of RSI sufferers have eliminated chronic pain by switching to the Evoluent VerticalMouse.

Trusted by Medical Professionals

Recommended by occupational therapists, hand surgeons, and ergonomists since 2002. The Evoluent VerticalMouse has helped tens of thousands of office workers, programmers, designers, and computer professionals eliminate chronic wrist pain and prevent surgery.

Who It's Built For

Essential for anyone experiencing wrist pain, forearm strain, carpal tunnel symptoms, or RSI from traditional mouse use. Ideal for office professionals, graphic designers, programmers, CAD operators, gamers, and anyone spending 4+ hours daily with a mouse. Particularly effective for post-injury recovery and preventing chronic conditions in high-risk computer users.

Technical Specifications

• Patented 78° vertical handshake angle
• Contoured ergonomic shape with extended lip
• 6 programmable buttons (left, right, middle, 2 thumb, 1 side)
• Adjustable DPI: 800/1300/1800/2600 (toggle button)
• Optical sensor for precise tracking
• USB wired connection (plug-and-play)
• Compatible with Windows, Mac, Linux
• Available in right-hand and left-hand versions
• Available in regular and small sizes
• Cable length: 6 feet

Size & Hand Selection Guide

Hand Size (measure from wrist crease to tip of middle finger):

• Small (VM4S): Up to 7 inches (178mm) - Ideal for smaller hands, youth, petite users
• Regular (VM4): 7+ inches (178mm+) - Standard size, fits majority of users

Hand Dominance:

• Right-Hand (VM4R): Most popular, designed for right-hand use
• Left-Hand (VM4L): Mirror design for left-handed users

What's Included

• Evoluent VerticalMouse 4
• USB cable (6 feet)
• Quick start guide
• Button programming instructions

Button Programming (Optional)

All 6 buttons are fully programmable using free Evoluent Mouse Manager software (Windows/Mac). Assign custom functions, keyboard shortcuts, or macros to any button for enhanced productivity. Works plug-and-play without software for standard mouse functions.

Adaptation Period

Most users adapt to vertical mouse positioning within 3-5 days. Start with short sessions (30-60 minutes) and gradually increase usage as your hand adjusts to the natural handshake position. Pain relief typically begins within the first week of consistent use, with maximum benefit achieved after 2-3 weeks.

Why Evoluent Outperforms Other Vertical Mice

Unlike generic vertical mice, the Evoluent features patented contoured shaping that prevents gripping, extended lip protection for pinky finger, and precision optical tracking. The 78° angle is clinically optimized for maximum forearm rotation relief without compromising usability. Over 20 years of ergonomic research and refinement make the Evoluent the gold standard in vertical mouse design.

Award-Winning Design

Winner of multiple ergonomic design awards including the Arthritis Foundation Ease-of-Use Commendation. Featured in ergonomic journals, medical publications, and recommended by leading hand surgeons and occupational health specialists worldwide.

Premium Quality & Warranty

Manufactured by Evoluent with rigorous quality control and durable construction. Each VerticalMouse 4 is backed by a 2-year manufacturer warranty and designed for years of daily professional use.

Frequently Asked Questions

How do I know which size to choose - regular or small?

Measure your hand from wrist crease to tip of middle finger. Choose Small (VM4S) if under 7 inches (178mm), Regular (VM4) if 7+ inches. When in doubt, choose Regular—the contoured shape accommodates a range of hand sizes. Most women prefer Small, most men prefer Regular.

Will this work for left-handed users?

Yes. The VerticalMouse 4 is available in dedicated left-hand (VM4L) and right-hand (VM4R) versions. The left-hand model is a true mirror design, not an ambidextrous compromise—providing optimal ergonomic support for left-handed users.

How long does it take to adjust to a vertical mouse?

Most users adapt within 3-5 days. Start with 30-60 minute sessions and gradually increase usage. Your hand needs time to adjust to the natural handshake position after years of pronated wrist positioning. Cursor precision typically returns to normal within 2-3 days.

Will this help with my carpal tunnel syndrome?

The VerticalMouse 4 is specifically designed to eliminate wrist pronation—the primary cause of carpal tunnel syndrome from mouse use. Thousands of users have eliminated carpal tunnel symptoms by switching to vertical positioning. However, consult your doctor for medical advice about existing conditions.

Can I use this for gaming or graphic design?

Yes. The VerticalMouse 4 provides precise optical tracking with adjustable DPI (800-2600) suitable for both gaming and design work. Many gamers and designers use vertical mice successfully. The 6 programmable buttons support custom macros and shortcuts.

Do I need to install software to use this mouse?

No. The VerticalMouse 4 works plug-and-play with standard mouse functions (left/right click, scroll, DPI toggle). Optional Evoluent Mouse Manager software (free download) enables advanced button programming and customization, but it's not required.

What's the difference between VerticalMouse 4 and VerticalMouse C?

The VerticalMouse 4 is wired USB with 6 programmable buttons and adjustable DPI. The VerticalMouse C is wireless with simplified 4-button design and fixed DPI. Choose VM4 for wired reliability and advanced features; choose VM-C for wireless convenience and simplicity.

Will the extended lip really prevent pinky dragging?

Yes. The extended lip is a key Evoluent innovation that prevents your pinky finger from dragging on the desk surface—a common source of friction and contact stress with traditional mice. This feature significantly reduces hand fatigue during extended use.

Why AskErgoWorks

As certified ergonomics specialists with over 30 years of experience, we've evaluated thousands of mice and helped hundreds of professionals eliminate wrist pain and RSI. The Evoluent VerticalMouse 4 consistently ranks as our top recommendation for users with carpal tunnel syndrome, wrist pain, or forearm strain—it's the original vertical mouse with over 20 years of proven clinical effectiveness.

We don't just sell ergonomic mice; we provide the expertise to ensure proper sizing, setup, and adaptation for maximum pain relief and productivity.

Need help choosing the right mouse or optimizing your workstation? Our ergonomic evaluation services include personalized mouse recommendations, hand size assessment, and complete workstation setup guidance based on your pain profile and work tasks.

Free shipping on orders over $50. 2-year warranty. Right & left hand options. Regular & small sizes available.